A Simple Key For cees dekker Unveiled
A Simple Key For cees dekker Unveiled
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2009, discovery of a brand new phenotype for bacteria in slim nanofluidic slits; and 1st detection of community protein buildings together DNA applying solid-point out nanopores
But how do morality, the dignity of your individual, my expertise from the meaning of lifetime, comply with through the movement of atoms? A purely naturalistic standpoint fails listed here; a Christian perspective, I do think, is a much more fair technique to interpret these elements of truth.’
Back again in 1991, Sumio Iijima with the NEC Company experienced described the synthesis of carbon nanotubes. Band framework calculations instructed that these nanotubes could show metallic band conduction. This would be a substantial advantage more than the conducting polymers we had explored, which were, actually, disordered semiconductors providing merely variable-variety hopping conductivity.
2007, very first serious-time detection of strand exchange in homologous recombination by RecA; discovery of a very low persistence length of ends of microtubules; and solved the system of biosensing with carbon nanotubes
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and 1st ever review in the dynamics DNA supercoils and the invention of supercoil hopping
Experimental phase diagram of negatively supercoiled DNA calculated by magnetic tweezers and fluorescence,
MATLAB codes for info processing are available at . Julia codes employed for numerical simulation are available at .
Atomic power microscopy demonstrates that vaccinia topoisomerase IB generates filaments on DNA inside a cooperative vogue
Understanding fundamental procedures regulating the spatial and dynamic organisation of the DNA in Reside cells.
‘The fantastically refined cees dekker way where aspects in character function never ceases to amaze me. If we address the puzzle of how lifetime came into being, I hope that my amazement for the complexity of development will have amplified and with it my awe to the greatness from the Creator.’
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Cees Dekker is Distinguished College Professor at TU Delft. Qualified being a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineteen nineties. Considering the fact that 2000, he moved to one-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, in particular SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is definitely an elected member from the KNAW and fellow towards the APS and also the IOP.
Developments in nanotechnology during the nineteen nineties built building electronic devices from one molecules a possibility. Cees Dekker recounts how his team created a room-temperature transistor depending on an individual carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and one-molecule experiments